What's behind natural ingredients?

Not too long ago, the medical community was treating natural products with a relative disdain. In it's almighty opinion, these products were to be classified with “alternative” practices in the best case and plain quack medicine in the worst.

Who could blame them? After all, when your white-haired family doctor was busy in Med School, he wasn't being taught about herbs and nature. It was all about chemicals and synthetic drugs : the pharmaceutical industry was in the middle of it's campaign to establish itself as the only reliable remedy to every ill.

Their marketing campaigns targeted doctors and pharmacists, as well as consumers. While the medical community was burried under samples, pamphlets and junket invitations, consumers learned to ask for drugs by their brand names to their doctors.

After years and millions of dollars invested to synthesize nature into mass-produced pills, the pharmaceutical industry was desperate for it's profit margin. After taking so much from plants and the environment, the only answer was to alienate human beings from nature.

Luckily, progressive doctors, researchers and consumers fought against the pharmaceutical industry's little white pills. By rediscovering nature through cutting edge technology and modern methodologies, natural products advocates established their credibility. Double-blind clinical tests proved that natural products are effective tools in the quest for a healthy lifestyle.

Today, the natural health industry is built on solid grounds. The production methods are optimal, the products are tested thoroughly and doctors are included in the process of research and development. What you buy today honestly doesn't have anything in common with your grandmother's remedies. As long as you respect the dosage, recommendations and counter-indications, natural products are safe for you to use.

L-Arginine

L-Arginine (6-7-8-16-19-20) is an amino acid that can be found naturally in almonds, dairy products or meat. These acids are the building blocks from which the body creates proteins needed for growth and repair in the human body. Among these, L-Arginine plays a vital part in the male sexuality by affecting erections and sperm production.

L-Arginine is an important source of nitrous oxide, which relaxes muscles and increases the blood flow to erectile tissues. Thus, L-Arginine can help men get stronger and harder erections more frequently.

As for sperm production, L-Arginine is a biochemical precursor in the synthesis of spermidine and spermine, two important components of semen. It also plays a helpful role in the cellular replication of semen.

Epimedium Sagittatum (Horny Goat Weed)

Originating from Japan, this plant is used in traditional Chinese medicine to treat erectile dysfunctions and to boost sperm production. Preliminary data hints the plant has effects on testosterone levels and blood vessels. Testosterone is a male hormone responsible in part for a person's sex drive and also influences sperm production. Also, Epimedium can inhibit the AchE enzyme, thus supporting higher levels of key choligernic nerotransmitters associated with sexual arousal. In studies (11), Epimedium was shown to benefit sex drive and erections.

Ginkgo Biloba

Ginkgo biloba (5) was almost wiped off the Earth during the ice age. Plants survived in Asia and were reintroduced in Europe around 1730. The Chinese traditionally used Ginkgo biloba for food and medicine. References to the plant can be found in treaties dating up to 2600 BC. European medicine only caught up around 1950. Amongst the fields of research, Ginkgo biloba was seen as a helpful tool in the fight against erectile dysfunctions.

60 subjects were followed between 12 and 18 months for an uncontrolled study(21). Each subject was supplemented with 60 mg of ginkgo biloba each day. The results indicated an improvement of erectile dysfunctions due to efficient circulations in erectile tissues. Another study(22) focused on erectile dysfunctions due to anti-depressants. Results indicated that a daily intake of 120 to 240 mg of ginkgo biloba had positive effects on the subjects' desire, sex drive, orgasm quality and general sexual satisfaction.

Panax Ginseng

Traditional Chinese medicine has offered a wide array of Ginseng treatments for sexual dysfunctions for over 2000 years. North American natives also used the local species of ginseng. Modern researchers believed Ginseng's effect on sexual function was hormonal. Recent studies showed the plant worked on the central nervous system and the testicals tissue.

In a 2002 double-blind clinical trial(23) with 45 subjects confirming that Ginseng, served in 3 daily doses of 900 mg, does better than a placebo..

In a double-blind clinical trial with placebo(12), 160 men suffering from premature ejaculation were given a topical cream which included ginseng in it's formula. Ejaculation was indeed retarded and further research is being conducted to better isolate the factors having contributed to this success, Ginseng amongst them.

Muira Pauma

Research from the Institute of Sexology, in Paris, focused on this Amazonian herb. Three studies, conducted by Dr Jacques Waynberg(13), established the credibility of Muira Pauma (Ptychopetalum olacoides) as a safe and effective tool to improve libido and sexual functions in subjects. Two clinical studies concentrated specifically on male sexual dysfunctions.

The first study followed 262 men with reduced sexual desire or erectile difficulties. After two weeks of treatment, 62% of subjects recognized a dynamic effect and 52% of subjects with erectile difficulties noted benefits.

As for his second study, entitled "Male Sexual Asthenia" Dr. Waynberg examined sexual troubles linked with asthenia, a condition marked by fatigue, lack of strength or debility. 100 men showing sings of impotence, loss of libido or both were included for the study. Of the 94 who completed the study, 66% noted a significant increase in their intercourse rate. 70% of the 46 men displaying a low libido showed an increase in their sex drive. Overall, 55% of patients displayed more stable erections during intercourse and 66% an increase in stamina.

Catuaba bark

The Tupi Indians of Brazil first discovered Catuaba's (also known as Catuama) aphrodisiac qualities. Today, Brazilian herbal medicine considers the plant as a central nervous system stimulant with aphrodisiac qualities. Catuaba's effects are considered important on male impotency, because it facilitates the bloodflow to the penis.

In 2001, Dr Antunes studied the relaxing effect of Catuaba on rabbit's cavernosal tissue. When this tissue is constricted, erection cannot occur. On humans, a study led by Dr Ghorayeb(14) indicated Catuaba helped increase erection, orgasms and ejaculations.

Males using Catuaba bark feel the effect on their libido, especially if used with Muira Puama.

Semen Cuscutae

The Cuscutae is also known as the Dodder. It'a parasitic wine, member of the convolvulaceae, with a long usage in Asia. The local varieties are the Cuscuta chinensis (China) and Cuscuta japonica (Japan). Dodders produce small brown seeds harvested for the concoction of herbal formulas.

Traditional Chinese Medicine attributes to the Dodder virtues in fighting impotence, nocturnal emissions, premature ejaculation and low sperm count. It is said to work very efficiently when combined to Epimedium Sagittatum. While we find wide empirical evidence in the wide traditional usage of the seed in Asia, modern science is rapidly catching up.

Tests have been conducted both on animals and humans. In China, a study(15) on humans linked Semen cuscutae to promotion of sperm motility and membrane functions. The researchers expressed high hopes for seeing the plant used to treat male sterility.

Fructus Crataegi

We can find Hawthorn in Western cultures from Greek antiquity, to the Middle-Ages and Renaissance. It was mostly recommended for the urinary system. In the 1930's the plant suddenly went out of style. Today, it has great popularity in Europe and is part of over 200 preparations. European clinical researchers tends to look towards the plant's interaction with the cardiovascular system. Chinese and American scientists are also following close with preliminary studies.

Zinc Oxyde

Zinc is an essential trace mineral and is linked to enzymatic functions. It has been also been found necessary for protein synthesis and carbohydrate metabolism.

The mineral is found in high concentrations in male ejaculate and plays an important role in prostate health. Frequent ejaculations have been recorded to lower Zinc presence in male's bodies. A low Zinc number is associated with poor sperm count and motility, especially when testosterone levels are low.

Dr Régine P.M. Steegers-Theunissen(16-19-20), an associate professor of obstetrics and gynecology at the University Medical Centre Nijmegen in The Netherlands wondered whether zinc and folic acid were important for male's healthy reproductive system. She set out to conduct a study with 211 men, of which 103 were subfertile. The subjects were randomly separated in three groups: one receiving Zinc, another a placebo and the last a combination of Zinc and a folic acid. Results showed all subjects receiving supplements have seen their sperm count increase massively.

DOSAGE

Quantities have purposely been omitted, serving per day is 2400mg

Bibliography

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  5. Ginkgo Biloba. Altern Med Rev. 1998;3(1):54-57.
  6. Appleton J. Arginine: Clinical potential of a semi-essential amino.Altern Med Rev. 2002 Dec;7(6):512-22.
  7. Scibona M, Meschini P, Capparelli S, et al. [L-arginine and male infertility]. [Article in Italian]. Minerva Urol Nefrol. 1994; 46:251-253.
  8. de Aloysio D, Mantuano R, Mauloni M, Nicoletti G. The clinical use of arginine aspartate in male infertility. Acta Eur Fertil 1982;13:133–67.
  9. Tanimura J. Studies on arginine in human semen. Bull Osaka Med School 1967;13:84–89.
  10. Hong B, Ji YH, Hong JH, Nam KY, Ahn TY. A double-blind crossover study evaluating the efficacy of korean red ginseng in patients with erectile dysfunction: a preliminary report. J Urol. 2002 Nov;168(5):2070-3.
  11. Lamm S, Couzens GS. Effect of Hony Goat Weed herbal complex supplement on sexual satisfaction in healthy men and men treated with Viagra. Unpublished preprint, 2001.
  12. Choi HK, Jung GW, Moon KH, Xin ZC, Choi YD, Lee WH, Rha KH, Choi YJ, Kim DK. Clinical study of SS-cream in patients with lifelong premature ejaculation.Urology 2000 Feb;55(2):257-61.
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  14. Ghorayeb, N. (n.d.). Catuama in the Erectile Dysfunction Syndrome. São Paulo, Brazil: Instituto Dante Pazzanese.
  15. Peng SJ, Lu RK, Yu LH. Effects of Semen cuscutae , rhizoma Curculiginis, radix Morindae officinalis on human spermatozoan's motility and membrane function in vitro. Institute of Reproductive Medicine, Wannan Medical College, Anhui Wuhu. Zhongguo Zhong Xi Yi Jie He Za Zhi. 1997 Mar;17(3):145-7.
  16. Wong WY, Merkus HM, Thomas CM, Menkveld R, Zielhuis GA, Steegers-Theunissen RP. Effects of folic acid and zinc sulfate on male factor subfertility: a double-blind, randomized, placebo-controlled trial. Fertil Steril. 2002 Mar;77(3):491-8.
  17. Hunt CD, Johnson PE, Herbel JoL, Mullen LK. Effects of dietary zinc depletion on seminal volume and zinc loss, serum testosterone concentrations, and sperm morphology in young men. Am J Clin Nutr 1992;56:148–57.
  18. Netter A, Hartoma R, Nahoul K. Effect of zinc administration on plasma testosterone, dihydrotestosterone and sperm count. Arch Androl 1981;7:69–73
  19. Wong WY, Flik G, Groenen PM, Swinkels DW, Thomas CM, Copius-Peereboom JH, Merkus HM, Steegers-Theunissen RP. The impact of calcium, magnesium, zinc, and copper in blood and seminal plasma on semen parameters in men. Reprod Toxicol. 2001 Mar-Apr;15(2):131-6.
  20. Wong WY, Thomas CM, Merkus JM, Zielhuis GA, Steegers-Theunissen RP. Male factor subfertility: possible causes and the impact of nutritional factors. Fertil Steril. 2000 Mar;73(3):435-42. Review.
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